Directed and illustrated by Shintaro Sakamoto From the album 'How to Live with a Phantom' Out on Other Music Recording Co. July 17, 2012 Shintaro Sakamoto begins a new and perhaps unexpected chapter in his storied career with the release of his debut solo album, the otherworldly folk-pop masterpiece How to Live with a Phantom. For over two decades Sakamoto was the frontman and leader of Japanese psychedelic phenomenon Yura Yura Teikoku, a Tokyo-based band that formed in 1989 as part of the burgeoning underground scene based around Koenji's legendary UFO Club, appearing on the PSF label's iconic Tokyo Flashback compilations and signing to the Captain Trip imprint. And yet across their 20-year trajectory, they rocketed out of the underground and achieved massive mainstream success throughout Japan with an always-evolving psych-pop sound that eventually found them working with Sony Music and headlining major music festivals across the country.

It was a rare case where great, boundary-breaking music resonated with the masses. While the group only ever played a handful of shows outside of their homeland, they achieved cult status throughout the world and saw several albums reissued in limited pressings in the U.S., including the critically acclaimed Hollow Me/Beautiful on James Murphy's DFA label. Immediately following Yura Yura Teikoku's break-up in 2010, Sakamoto began recording as a solo artist - truly solo, he plays all the instruments here save percussion and woodwinds - and after more than a year holed up in his home studio, How to Live with a Phantom was born. The resulting album is a bold stylistic departure, even for an artist whose career has been defined by them. It is a single-minded exploration of the sounds of 1970s radio pop from around the globe, combining American folk-rock and the evocative Japanese pop music that was influenced by it, but simultaneously referencing everything from French pop to Afro-funk, tropicalia, Krautrock and the lighter side of psychedelia. Most of the songs are built around Sakamoto's hypnotic electric-bass grooves (he learned to play for these recordings), a crisp drum set and bubbling percussion, layered with dreamy guitars and vintage synthesizers, and topped by meticulously arranged female vocal harmonies, horns, and Sakamoto's own languid yet deeply expressive lead vocals. Madden 2004 Pc Full Version Download.

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It's a set that's both sun-drenched and full of melancholy, and while the musical references and inspirations may be clear, How to Live with a Phantom is a wholly original album that will connect to a broad spectrum of listeners - from folk and pop aficionados to world music fans, psych-heads and many more. We could not be more excited to be releasing How to Live with a Phantom as Other Music Recording Co.' S debut full-length, and we know you will be as moved by this record as we are.

Adobe Flash Player is required to view this feature. If you are using an operating system that does not support Flash, we are working to bring you alternative formats. Original Article High Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis Hideaki Hamano, M.D., Shigeyuki Kawa, M.D., Akira Horiuchi, M.D., Hiroshi Unno, M.D., Naoyuki Furuya, M.D., Taiji Akamatsu, M.D., Mana Fukushima, M.D., Toshio Nikaido, Ph.D., Kohzo Nakayama, Ph.D., Nobuteru Usuda, M.D., and Kendo Kiyosawa, M.D. N Engl J Med 2001; 344:732-738 DOI: 10.1056/NEJM41005. Results The median serum IgG4 concentration in the patients with sclerosing pancreatitis was 663 mg per deciliter (5th and 95th percentiles, 136 and 1150), as compared with 51 mg per deciliter (5th and 95th percentiles, 15 and 128) in normal subjects (P. Figure 2 Findings on Endoscopic Retrograde Cholangiopancreatography and Ultrasonography (Insets) in a 72-Year-Old Woman with Sclerosing Pancreatitis. Before therapy (Panel A), there is irregular narrowing of the main pancreatic duct and sonolucent swelling of the pancreas.

The dimension of the main pancreatic duct (D1) is 1.2 mm, and the dimension of the pancreatic body (D2) is 14.0 mm. After four weeks of glucocorticoid therapy (Panel B), the abnormalities have resolved. The dimension of the pancreatic head (D1) is 9.7 mm, and the dimension of the pancreatic body (D2) is 8.7 mm. Laboratory Tests Because there is no widely accepted method of measuring the concentrations of subclasses of IgG, we measured serum IgG4 and the other subclasses of IgG in the patients with sclerosing pancreatitis and the normal subjects using two methods: single radial immunodiffusion (Binding Site, Birmingham, United Kingdom) and enzyme-linked immunosorbent assay (ELISA) (Yoshitomi Pharmaceutical Industries, Osaka, Japan). We found a close correlation between the results of single radial immunodiffusion and those of ELISA for each serum IgG subclass. Serum IgG4 concentrations in the other patients were measured by single radial immunodiffusion. Serum total IgG, IgA, and IgM concentrations were measured by turbidimetric immunoassay, and serum IgE concentrations were measured by ELISA.

We determined the cutoff values for serum IgG4 and IgG by analyzing receiver-operating-characteristic curves. We measured circulating immune complexes with an ELISA kit with monoclonal rheumatoid factor (Immune complex mRF Nissui, Nissui Pharmaceutical, Tokyo, Japan). We used the manufacturer's recommended cutoff value, which was the mean plus 2 SD of values in normal subjects. To detect circulating immune complexes containing IgG4, we designed a new ELISA system using monoclonal rheumatoid factor–coated plates and peroxidase-labeled antihuman IgG4 antibody (AU009, Binding Site) as a tracer antibody. This antihuman IgG4 antibody was the same as that used in single radial immunodiffusion for IgG4. The serum samples were treated with EDTA solution according to the instructions for the circulating immune-complex–assay system.

Peroxidase-labeled antihuman IgG4 antibody was diluted 1:5000 with phosphate-buffered saline containing 0.5 percent bovine serum albumin, and specimens were stained with 3,3',5,5'-tetramethylbenzidine (Behring Diagnostics, Marburg, Germany). Optical density was measured at 450 nm with a microplate reader (Bio-Rad Laboratories, Hercules, Calif.). We tentatively defined the cutoff value for the serum concentration of the IgG4 subclass of immune complexes as an optical-density unit of 0.1, because serum samples from all 20 normal subjects had lower values. Statistical Analysis Statistical analyses were performed with the Mann–Whitney test to compare the serum concentrations of each IgG subclass, IgA, IgM, and IgE in patients with sclerosing pancreatitis with those in normal subjects. The Wilcoxon matched-pairs signed-rank test was used to compare serum IgG concentrations, serum IgG4 concentrations, the ratio of serum IgG4 to serum IgG, serum concentrations of circulating immune complexes, and serum concentrations of the IgG4 subclass of circulating immune complexes in patients with sclerosing pancreatitis before and after four weeks of glucocorticoid therapy.

Data were analyzed with the use of SPSS software (version 6.1, SPSS, Chicago). All reported P values are two-sided.

To differentiate sclerosing pancreatitis from other pancreatic diseases (ordinary chronic pancreatitis and pancreatic cancer), we analyzed receiver-operating-characteristic curves for serum IgG and IgG4 values with the use of the statistical software package Stat Flex (version 5.0, Artech, Osaka, Japan). Results According to both assay methods, the patients with sclerosing pancreatitis had serum IgG4 concentrations that were significantly higher than those in the normal subjects (P. Supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture of Japan (11877089). We are indebted to Ms.

Sachiko Akanuma and Mr. Hiroya Hidaka of Central Clinical Laboratories for technical assistance with the serum IgG4 determinations; to Dr. Eiji Tanaka, Dr. Kaname Yoshizawa, Dr. Tetsuya Ichijyo, and Dr. Akihiro Matsumoto of the Second Department of Internal Medicine for assistance with sample collection and statistical analysis; to Ms. Ayumi Nakazawa of the Department of Anatomy for technical assistance with histologic analysis; to Dr.

Osamu Hasebe, Dr. Masuo Tokoo, and Dr.

Seiichi Furuta of Nagano Municipal Hospital, Dr. Kenji Matsuzawa of Maruko Central Hospital, Dr. Kenji Mukawa of Suwa Red Cross Hospital, Dr. Shinya Maejima of Chushin Matsumoto Hospital, and Dr.

Yoshiyuki Nakamura and Dr. Shinji Okaniwa of Iida Municipal Hospital for clinical assistance; and to Dr. Kiyoshi Ichihara of Kawasaki Medical School for assistance with the statistical analysis. Source Information From the Second Department of Internal Medicine (H.H., S.K., A.H., H.U., N.F., T.A., K.K. Lick Library Oasis Download Metallica One. ) and the Departments of Laboratory Medicine (M.F.), Obstetrics and Gynecology (T.N.), Organ Generation (T.N.), and Anatomy (K.N.), Shinshu University School of Medicine, Matsumoto, Japan; and the Department of Anatomy, Fujita Health University School of Medicine, Toyoake, Japan (N.U.).

Address reprint requests to Dr. Kawa at the Second Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan,.